Preheat oven to 350 degrees and line a baking sheet with parchment paper
In a medium bowl, beat together the softened cream cheese and cranberry sauce.
Using a large knife, cut the entire block of Hawaiian rolls in half.
Spread the cream cheese mixture over the top half of the rolls. Place the sliced turkey on top of the bottom half of rolls. Carefully place the top half on top of the turkey slices.
In a small bowl, combine the melted butter, garlic powder, onion powder, and Worcestershire sauce. Whisk to combine, then spread the mixture over the top of the sandwiches.
Bake in the preheated oven for 15 minutes, or until the cheese begins to melt and the top of the sliders is golden brown.